History of medical technology

123 inventions by year: what each evolved from and what it led to.

YearInventionWhat it isEvolved fromLed to
3000 BCCatheter
Michele Troja
A tube inserted into a body cavity.
3000 BCScalpelA surgical knife.Knife
3000 BCSurgical sutureStitching tissue with thread.Surgical stapler
2800 BCCrutchesSupports for walking.Wheelchair
1500 BCBandageDressing material.Sticking plaster
1000 BCStretcherA means of carrying the wounded.
950 BCProsthetic limbAn artificial replacement for a limb; modern ones are bionic.
700 BCDenturesRemovable artificial teeth.
100 BCSurgical forcepsTongs for grasping tissue.Haemostat
1286GlassesLenses for correcting vision (Italy).Magnifying glassSunglasses, Contact lens, Telescope, Microscope
1286Spectacle frameA holder for lenses.
1655WheelchairA chair on wheels; the self-propelled one — Farffler.Crutches
1718TourniquetA means of stopping bleeding (Petit; Esmarch’s tourniquet).
1796Vaccine
Edward Jenner
Preventing a disease with a weakened pathogen (Jenner).
1796Smallpox vaccine
Edward Jenner
Vaccination with cowpox (Jenner).
1806EndoscopeViewing internal organs; the flexible fibre-optic one dates from 1957.
1816Stethoscope
René Laenne
An instrument for listening to the heart and lungs (Laennec).
1818Blood transfusionThe first successful one — Blundell; blood groups — Landsteiner, 1901.
1819Dental fillingAmalgam, then composites.
1831IV dripIntravenous infusion of solutions (Latta).
1834CapsuleA gelatin capsule (Mothes).
1838OtoscopeAn instrument for examining the ear.
1843Tablet (medicine)A pressed dosage form (Brockedon).
1846General anaesthesiaEther anaesthesia for surgery (Morton; Pirogov).
1851Ophthalmoscope
Hermann von Helmholtz
An instrument for examining the back of the eye (Helmholtz).
1852Plaster cast
Antonius Mathijsen
Immobilizing fractures with plaster (Mathijsen, Pirogov).
1853SyringeAn instrument for injections (Wood, Pravaz).
1858NebulizerA medication sprayer.
1861Germ theory of disease
Germ theory's key 19th century figures, Louis Pasteur
Diseases are caused by microorganisms (Pasteur, Koch).
1867Clinical thermometerAllbutt’s thermometer for measuring body temperature.Digital thermometer
1867AntisepsisDisinfecting wounds and instruments (Lister).Sterilization
1871Dental drillA dentist’s drill (Morrison; the turbine drill in 1957).
1879Autoclave
Charles Chamberland
Sterilizing with steam under pressure (Chamberland).
1880HaemostatA clamp for blood vessels (Kocher, Péan).Surgical forceps
1880Infant incubatorAn incubator for premature babies (Tarnier).Incubator
1880SterilizationKilling microorganisms on instruments.Antisepsis
1882Culture medium (agar)Agar for growing bacteria (Hesse, Koch).
1884Gram staining
Hans Christian Gram
A method for telling bacteria apart.
1884Local anaesthesiaCocaine (Koller), then novocaine (1905).
1885Rabies vaccinePasteur’s vaccine.
1888Reflex hammerA small hammer for testing reflexes.
1888First aid kitA first aid set (Johnson & Johnson).
1890AntibodiesProteins of the immune system (Behring, Ehrlich).
1890Surgical glovesRubber gloves (Halsted).
1896X-ray machineImages of internal organs.CT scanner
1896Blood pressure monitorMeasuring blood pressure (Riva-Rocci; Korotkov’s method).ManometerDigital blood pressure monitor
1896Dental X-rayImages of the teeth.
1896Radiation therapyTreating tumours with radiation.
1897Surgical maskA surgeon’s mask (Mikulicz).Respirator
1897Aspirin
Raffaele Piria, Adolph Wilhelm Hermann Kolbe
Acetylsalicylic acid (Hoffmann, Bayer).
1898Hearing aidAn electronic sound amplifier for people with hearing loss.Telephone
1899AmbulanceA vehicle for transporting patients.Truck
1901Blood groups
Karl Landsteiner
The ABO system (Landsteiner).
1903ElectrocardiographRecording the electrical activity of the heart (Einthoven).GalvanometerHolter monitor
1908Surgical staplerA device for joining tissue with staples (Hültl).Surgical suture
1908Water chlorinationDisinfecting drinking water with chlorine.
1909Hospital bedAn adjustable bed (Gatch).
1910RespiratorA filtering mask (the anti-plague mask — Wu Lien-teh).Surgical maskGas mask
1910LaparoscopyOperating through small punctures with a camera.
1917Anaesthetic machine
Otto Roth, Heinrich Dräger
Boyle’s machine for delivering gases.
1917Air ambulanceEvacuating patients by aeroplane and helicopter.
1920Sticking plasterA plaster with a gauze pad (Band-Aid, Dickson).Bandage
1921Operating microscopeA microscope for microsurgery.
1922InsulinA hormone for treating diabetes (Banting, Best).
1922AudiometerAn instrument for testing hearing.
1924ElectroencephalographRecording the electrical activity of the brain (Berger).
1928VentilatorMechanical ventilation of the lungs (the “iron lung”).
1928AntibioticFleming’s penicillin and the drugs that followed.
1928Penicillin
Alexander Fleming
The first antibiotic (Fleming; production — Florey, Chain).
1935SulfonamidesThe first synthetic antibacterial drugs (Domagk).Synthetic dye
1937Blood bank
Charles Drew
Storing donor blood with an anticoagulant.
1943Haemodialysis machine
Willem Johan Kolff
An artificial kidney (Kolff).
1943Streptomycin
Albert Schatz
An antibiotic against tuberculosis (Waksman, Schatz).
1947DefibrillatorAn electric shock to restore the heart’s rhythm.Implantable defibrillator
1949Contact lensA lens worn on the cornea.Glasses
1949Lens replacementAn artificial intraocular lens (Ridley).
1950Cold chainKeeping vaccines at low temperature.
1950ElectromyographyRecording the electrical signals of muscles.
1953Medical linear acceleratorA linear accelerator for radiation therapy.
1953Heart–lung machineTakes over the heart and lungs during surgery (Gibbon; Bryukhonenko).Artificial heart
1954Organ transplantationA kidney transplant (Murray).
1955Polio vaccine
Jonas Salk
Salk; the live vaccine — Sabin, Chumakov.
1956InhalerA metered-dose aerosol (Riker).
1956Ultrasound scannerImaging organs by reflected ultrasound.
1957Gamma cameraScintigraphy of radioactive tracers (Anger).
1958PacemakerAn implanted pulse generator for the heart.Implantable defibrillator
1960Artificial heart valveA mechanical valve (Starr–Edwards).
1960Cardiopulmonary resuscitationChest compressions and rescue breathing (Kouwenhoven, Safar).
1960TelemedicineMedical care at a distance.
1962Holter monitor
Norman Holter
Recording an ECG over 24 hours (Holter).Electrocardiograph
1962Joint replacementAn artificial hip joint (Charnley).
1963Laser surgeryOperations with a laser beam (vision correction).
1966MammographX-ray imaging of the breast.
1968Gamma KnifeRadiosurgery with beams of gamma rays (Leksell).
1970Glucose meterMeasuring blood sugar.Continuous glucose monitoring
1970Digital thermometerA thermometer with a thermistor.Clinical thermometer
1970Oxygen concentratorA device that extracts oxygen from the air.
1971CT scannerSlice-by-slice X-ray images assembled by a computer (Hounsfield).X-ray machine
1973Recombinant DNAGenetic engineering (Cohen, Boyer).CRISPR
1974Pulse oximeterMeasures blood oxygen saturation with light (Aoyagi).
1975PET scannerPositron emission tomography.
1976Insulin pumpA wearable insulin dispenser.
1977DNA sequencingReading the sequence of DNA (Sanger).
1977Pregnancy testAn immunochromatographic strip.Rapid test
1977MRIImaging based on nuclear magnetic resonance.
1977AngioplastyWidening a vessel with a balloon (Grüntzig).
1978Cochlear implant
William F. House
Electrodes stimulate the auditory nerve.
1980Implantable defibrillatorA cardioverter under the skin (Mirowski).Defibrillator, Pacemaker
1980LithotripsyBreaking up stones with shock waves.
1981Digital blood pressure monitorAn automatic oscillometric monitor.Blood pressure monitor
1982Artificial heartA mechanical pump instead of the heart (Jarvik-7).Heart–lung machine
1983PCRThe polymerase chain reaction — copying DNA (Mullis).
1986StentA mesh frame that widens a blood vessel.
1988Rapid testAn antigen strip — the same principle as a pregnancy test.Pregnancy test
1998Brain–computer interfaceControlling devices with brain signals.
1999Continuous glucose monitoringA wearable sugar sensor.Glucose meter
2000Surgical robotA robotic manipulator for operations (da Vinci).Industrial robot
2003Human Genome ProjectReading the human genome.
2007Bionic handA prosthesis with myoelectric control.
2009Fitness trackerA wearable activity and heart-rate sensor.Smartwatch
2011ExoskeletonA wearable robot for walking (ReWalk).
2012CRISPRGenome editing (Doudna, Charpentier).Recombinant DNA
2020mRNA vaccine
Katalin Karikó, Drew Weissman
A vaccine that delivers instructions for making an antigen.

See also

Open Evothings